Does azithromycin affect INR?
Azithromycin is considered unlikely to interact with warfarin. Unlike other macrolide antibiotics, it is not hepatically metabolized and did not produce an interaction with warfarin in a single-dose study. Close monitoring of INR is recommended, and warfarin dosage adjustment may be necessary.Click to see full answer. Keeping this in consideration, do antibiotics increase INR?Antibiotics in…
Azithromycin is considered unlikely to interact with warfarin. Unlike other macrolide antibiotics, it is not hepatically metabolized and did not produce an interaction with warfarin in a single-dose study. Close monitoring of INR is recommended, and warfarin dosage adjustment may be necessary.Click to see full answer. Keeping this in consideration, do antibiotics increase INR?Antibiotics in the same class have similar effects on INR: Cephalosporins may increase INR by inhibiting production of vitamin K-dependent clotting factors. Macrolides and metronidazole may increase INR by inhibiting warfarin’s metabolism.Secondly, does Keflex increase INR? Cephalexin may increase the effects of warfarin and cause you to bleed more easily. You may need more frequent monitoring of your INR after starting cephalexin or whenever it is discontinued, and appropriate adjustments made in your dosage if necessary. Similarly, does azithromycin thin your blood? Azithromycin can also increase the effects of blood thinners such as warfarin. Other drugs that may interact with azithromycin include: digoxin, a heart medication. colchicine, a gout medication.What medications affect INR?Drugs that can decrease warfarin effect & lower INR in some pts include antacids, antihistamines, barbiturates, rifampin, sucralfate, trazodone, carbamazepine, cholestyramine, griseofulvin, haloperidol, oral contraceptives, penicillin, dicloxacillin, and nafcillin.
