How is replication regulated in eukaryotes?
Eukaryotic DNA replication is regulated to ensure all chromosomes replicate once and only once per cell cycle. Cell cycle regulation by protein phosphorylation ensures that pre-RC assembly can only occur in G1 phase, whereas helicase activation and loading can only occur in S phase.Click to see full answer. Also question is, how do eukaryotic cells…
Eukaryotic DNA replication is regulated to ensure all chromosomes replicate once and only once per cell cycle. Cell cycle regulation by protein phosphorylation ensures that pre-RC assembly can only occur in G1 phase, whereas helicase activation and loading can only occur in S phase.Click to see full answer. Also question is, how do eukaryotic cells replicate?Explanation: Most Eukaryotic cells reproduce by mitosis. It involves replication of DNA first then, nuclear division and then cell division. The two daughter cells and identical to the mother cell with same number of chromosomes.Secondly, how is replication different in prokaryotes and eukaryotes? In prokaryotic cells, there is only one point of origin, replication occurs in two opposing directions at the same time, and takes place in the cell cytoplasm. Lastly, the short replication in prokaryotes occurs almost continuously, but eukaryotic cells only undergo DNA replication during the S-phase of the cell cycle. Secondly, what initiates DNA replication in eukaryotes? Initiation. Initiation of eukaryotic DNA replication is the first stage of DNA synthesis where the DNA double helix is unwound and an initial priming event by DNA polymerase α occurs on the leading strand. Priming of the DNA helix consists of synthesis of an RNA primer to allow DNA synthesis by DNA polymerase α.How are eukaryotic chromosomes replicated?Eukaryotic DNA is bound to proteins known as histones to form structures called nucleosomes. During initiation, the DNA is made accessible to the proteins and enzymes involved in the replication process. There are specific chromosomal locations called origins of replication where replication begins.
