Is adiponectin an Adipokine?
Adiponectin is a recently described adipokine that has been recognized as a key regulator of insulin sensitivity and tissue inflammation. In contrast to other adipokines, adiponectin secretion and circulating levels are inversely proportional to body fat content.Click to see full answer. Regarding this, what is adiponectin function?Adiponectin is a protein hormone that modulates a number…
Adiponectin is a recently described adipokine that has been recognized as a key regulator of insulin sensitivity and tissue inflammation. In contrast to other adipokines, adiponectin secretion and circulating levels are inversely proportional to body fat content.Click to see full answer. Regarding this, what is adiponectin function?Adiponectin is a protein hormone that modulates a number of metabolic processes, including glucose regulation and fatty acid oxidation. Adiponectin is secreted from adipose tissue (and also from the placenta in pregnancy) into the bloodstream and is very abundant in plasma relative to many hormones.Subsequently, question is, is adiponectin a cytokine? Adipocytokines are classified as cytokines that are mainly, but not exclusively, produced by adipose tissue. Leptin and adiponectin constitute adipocytokines that are believed to mediate insulin resistance and related inflammatory disorders (La Cava and Matarese 2004; Wellen and Hotamisligil 2005). Similarly, is insulin an Adipokine? Apparently, increased TNF-α and IL-6 expression and secretion from adipose tissue are involved in both whole-body and local insulin resistance at different tissue sites. On the other hand, adiponectin induces insulin sensitivity, and is the only adipokine known to decrease obesity-related insulin resistance.What are adipokines and cytokines?The adipokines, or adipocytokines (Greek adipo-, fat; cytos-, cell; and -kinos, movement) are cytokines (cell signaling proteins) secreted by adipose tissue. Since that time, hundreds of adipokines have been discovered. Members include: Leptin.
