Is epinephrine given subcutaneously?

The product label of EpiPen, the only autoinjection epinephrine product approved in the US for anaphylaxis, recommends IM intramuscular injection into the anterolateral aspect of the thigh, but it also states that epinephrine, when given intramuscularly or subcutaneously, has a rapid onset of action, which supportsClick to see full answer. Just so, why is adrenaline given subcutaneously?Adrenaline also alleviates pruritus, urticaria and angioedema associated with anaphylaxis. Adrenaline has a rapid onset of action after intramuscular administration and in the shocked patient its absorption from the intramuscular site is faster and more reliable than from the subcutaneous site.Additionally, is an EpiPen subcutaneous or intramuscular? Inject EpiPen or EpiPen Jr intramuscularly or subcutaneously into the anterolateral aspect of the thigh, through clothing if necessary. Each EpiPen or EpiPen Jr Auto-Injector contains a single dose of epinephrine. Moreover, how can epinephrine be administered? Epinephrine injection comes as a prefilled automatic injection device containing a solution (liquid) and in vials to inject subcutaneously (under the skin) or intramuscularly (into the muscle). It is usually injected as needed at the first sign of a serious allergic reaction.Why is epinephrine injected in the thigh?A: The recommendation for injecting epinephrine in the lateral thigh is to facilitate most rapidly achieving epinephrine in the peripheral blood to combat anaphylaxis. The greater vascularity of muscle makes IM injection preferable to SQ injection.