What does 17 alpha hydroxylase do?

The enzyme has 17 alpha(α)-hydroxylase activity, which is important for production of glucocorticoids and sex hormones. CYP17A1 also has 17,20-lyase activity, which is integral to the production of sex hormones. 17α-hydroxylase/17,20-lyase deficiency results from a shortage (deficiency) of both enzyme activities.Click to see full answer. Similarly, what is hydroxylase deficiency?21-hydroxylase deficiency is an inherited disorder that affects the adrenal glands. In people with 21-hydroxylase deficiency, the adrenal glands produce excess androgens, which are male sex hormones. There are three types of 21-hydroxylase deficiency.One may also ask, what is p450c17 enzyme deficiency? The characteristics of P450c17 deficiency include 46,XY disorder of sex development, hypertension, hypokalemia, and lack of pubertal development. To better understand this rare enzymatic deficiency, we analyzed the CYP17A1 gene in six affected patients. Consequently, what does the cyp17 gene do? CYP17A1 is a member of the cytochrome P450 superfamily of enzymes localized in the endoplasmic reticulum. Proteins in this family are monooxygenases that catalyze synthesis of cholesterol, steroids and other lipids and are involved in drug metabolism. CYP17A1 has both 17α-hydroxylase activity and 17,20-lyase activity.Is congenital adrenal hyperplasia a disability?Specific learning disabilities have been rarely reported in congenital adrenal hyperplasia. The impact of hormones on cognition is still not clearly defined, but it is postulated that females with this condition have excess prenatal androgen stimulation, which increases the risk for cognitive impairment.