What is Adipokines function?

Adipokines, that is factors secreted by adipose tissue, act through a network of autocrine, paracrine, and endocrine pathways to regulate several aspects of physiology, including glucose and lipid metabolism, neuroendocrine function, reproduction, and cardiovascular function.Click to see full answer. Similarly, what are adipokines and cytokines?The adipokines, or adipocytokines (Greek adipo-, fat; cytos-, cell; and -kinos,…

Adipokines, that is factors secreted by adipose tissue, act through a network of autocrine, paracrine, and endocrine pathways to regulate several aspects of physiology, including glucose and lipid metabolism, neuroendocrine function, reproduction, and cardiovascular function.Click to see full answer. Similarly, what are adipokines and cytokines?The adipokines, or adipocytokines (Greek adipo-, fat; cytos-, cell; and -kinos, movement) are cytokines (cell signaling proteins) secreted by adipose tissue. Since that time, hundreds of adipokines have been discovered. Members include: Leptin.Beside above, which Adipokine promotes inflammation and causes insulin resistance? Adipose tissue secretes various pro- and anti-inflammatory adipokines to modulate inflammation and insulin resistance. In obese humans and rodent models, the expression of pro-inflammatory adipokines is enhanced to induce insulin resistance. Beside this, is leptin an Adipokine? Leptin is an adipokine with central importance in the global obesity problem and consequent cardiovascular disease and is principally secreted by adipocytes and acts in the hypothalamus to suppress appetite and food intake, increase energy expenditure, and regulate body weight.Is insulin an Adipokine?Apparently, increased TNF-α and IL-6 expression and secretion from adipose tissue are involved in both whole-body and local insulin resistance at different tissue sites. On the other hand, adiponectin induces insulin sensitivity, and is the only adipokine known to decrease obesity-related insulin resistance.

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