What is the difference between vancomycin trough and random level?
Trough concentrations are recommended for therapeutic monitoring of vancomycin, preferably acquired at steady state (just before fourth dose). Random levels may be ordered when attempting to determine when to dose vancomycin in patients with renal impairment or those undergoing dialysis.Click to see full answer. Accordingly, what is vancomycin random level?Vancomycin, Random Level. Vancomycin is an…
Trough concentrations are recommended for therapeutic monitoring of vancomycin, preferably acquired at steady state (just before fourth dose). Random levels may be ordered when attempting to determine when to dose vancomycin in patients with renal impairment or those undergoing dialysis.Click to see full answer. Accordingly, what is vancomycin random level?Vancomycin, Random Level. Vancomycin is an antibiotic which is used for the treatment of infections caused by Gram-positive organisms, primarily methicillin resistant Staphylococcus aureus (MRSA), coagulase-negative Staphylococci, Streptococci or Enterococci, particularly in patients allergic to β-lactams.Likewise, what happens if vancomycin trough is high? Recent guidelines have recommended vancomycin trough levels of 15–20 mg/L for treatment of serious infections caused by methicillin-resistant Staphylococcus aureus (MRSA). However, high trough levels may increase risk of nephrotoxicity and mortality, and high vancomycin trough levels have not been well studied. Furthermore, what is a vancomycin trough? When a person takes a dose of vancomycin, the amount in the blood rises for a period of time, peaks, and then begins to fall, usually reaching its lowest level, or trough, just before the next dose. The next dose is timed to coincide with the falling concentration of the drug in the blood.When should trough levels be drawn?A trough level is drawn immediately before the next dose of the drug is administered. A peak level is drawn 1 to several hours after the drug is administered (depending on the drug).
