What is Valinomycin used for?
Valinomycin is a potent antibiotic. It is commonly used as an agent to induce apoptosis and can also be used to calibrate potentiometric responses in membrane experiments involving potential-sensitive dyes such as di-4-ANEPPS. For Research Use Only. Not for human or animal therapeutic or diagnostic use.Click to see full answer. Also know, what role is…
Valinomycin is a potent antibiotic. It is commonly used as an agent to induce apoptosis and can also be used to calibrate potentiometric responses in membrane experiments involving potential-sensitive dyes such as di-4-ANEPPS. For Research Use Only. Not for human or animal therapeutic or diagnostic use.Click to see full answer. Also know, what role is played by Valinomycin?Valinomycin is highly selective for potassium ions over sodium ions within the cell membrane. It functions as a potassium-specific transporter and facilitates the movement of potassium ions through lipid membranes “down” the electrochemical potential gradient.Beside above, how does an ionophore work? An ionophore is a chemical species that reversibly binds ions. Many ionophores are lipid-soluble entities that transport ions across a cell membrane. Some ionophores are synthesized by microorganisms to import ions into their cells. Synthetic ion carriers have also been prepared. Regarding this, how does Valinomycin affect cellular respiration? mitochondria, eliminating respiratory control. Valinomycin produces higher steady state potassium phosphate swelling which can be reversed to give active shrinkage if mersalyl is added to block the Pi−/OH− antiporter. Respiration declines concurrently. Uncouplers accelerate the shrinkage and restore the respiration.What is an ionophore antibiotic?Ionophore. Ionophores (such as monensin) are antimicrobials fed to cattle to improve production efficiency that are unrelated to antibiotics used in human medicine. From: Advances in Microbial Food Safety, 2013.
