Can warfarin cause hypothyroidism?

The authors found that the effects of liver disease, hyperthyroidism and hypothyroidism on the response to warfarin are well documented in the literature. In hypothyroid states, decreased catabolism of vitamin K–dependent clotting factors is believed to cause the decreased response to oral anticoagulants.Click to see full answer. Furthermore, can warfarin affect thyroid function?Among diseases that…

The authors found that the effects of liver disease, hyperthyroidism and hypothyroidism on the response to warfarin are well documented in the literature. In hypothyroid states, decreased catabolism of vitamin K–dependent clotting factors is believed to cause the decreased response to oral anticoagulants.Click to see full answer. Furthermore, can warfarin affect thyroid function?Among diseases that are well-documented to have a clinically relevant effect on response to warfarin are hyperthyroidism and hypothyroidism. Hyperthyroidism increases response to warfarin by increasing catabolism of vitamin K dependent clotting factors.Similarly, does thyroid medication thin blood? No, it’s not a blood thinner, an antidepressant or a cholesterol-lowering drug—it’s Synthroid, a medication used to treat underactive thyroid (hypothyroidism). In this regard, does levothyroxine interfere with warfarin? There are basically 2 possible explanations for these results: 1) in clinically hypothyroid individuals taking warfarin, adding levothyroxine does not affect the anticoagulant response to warfarin, or 2) initiation of levothyroxine in individuals with hypothyroidism does increase warfarin response, but for 1 or moreHow does amiodarone cause hypothyroidism?Amiodarone causes a wide spectrum of effects on the thyroid. The response of TSH to thyroid-releasing hormone (TRH) may be reduced. Amiodarone and its metabolites may have a direct cytotoxic effect on the thyroid follicular cells, which causes a destructive thyroiditis.

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