What causes primary polycythemia?

Primary polycythemias are due to acquired or inherited genetic mutations causing abnormally high levels of red blood cell precursors. Primary familial and congenital polycythemia (PFCP) and polycythemia vera (PV) are in this category.Click to see full answer. Likewise, what causes secondary polycythemia?Secondary polycythemia most often develops as a response to chronic hypoxemia, which triggers increased…

Primary polycythemias are due to acquired or inherited genetic mutations causing abnormally high levels of red blood cell precursors. Primary familial and congenital polycythemia (PFCP) and polycythemia vera (PV) are in this category.Click to see full answer. Likewise, what causes secondary polycythemia?Secondary polycythemia most often develops as a response to chronic hypoxemia, which triggers increased production of erythropoietin by the kidneys. 25 The most common causes of secondary polycythemia include obstructive sleep apnea, obesity hypoventilation syndrome, and chronic obstructive pulmonary disease (COPD).Beside above, what are the two types of polycythemia? There are two main types of polycythemia: primary and secondary. The first is usually caused by a genetic mutation, whereas the latter is caused by an underlying condition that either prevents oxygen delivery to tissues (for example, a lung or heart condition), or a tumor that affects secretion of erythropoietin. Likewise, people ask, how is primary polycythemia treated? Common medicines: Chemotherapy —Lowers blood cell production, controls blood volume, and improves your immune system. JAK inhibitors—Reduces spleen size and improves the balance of other blood cells. Low-dose aspirin—Thins blood to reduce the risk of blood clots. Don’t take aspirin without talking to your doctor. Is Polycythemia a cancer?Polycythemia vera (pol-e-sy-THEE-me-uh VEER-uh) is a type of blood cancer. It causes your bone marrow to make too many red blood cells. These excess cells thicken your blood, slowing its flow, which may cause serious problems, such as blood clots. Polycythemia vera is rare.

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