Which drugs cause neuroleptic malignant syndrome?

NMS is usually caused by antipsychotic drug use, and a wide range of drugs can result in NMS. Individuals using butyrophenones (such as haloperidol and droperidol) or phenothiazines (such as promethazine and chlorpromazine) are reported to be at greatest risk.Click to see full answer. Just so, what medications are commonly implicated in NMS?In more severe cases of NMS, empiric pharmacologic therapy is typically tried. The two most frequently used medications are bromocriptine mesylate, a dopamine agonist, and dantrolene sodium, a muscle relaxant that works by inhibiting calcium release from the sarcoplasmic reticulum.Additionally, is neuroleptic malignant syndrome permanent? Neuroleptic malignant syndrome (NMS) is a neurologic emergency condition that may arise as a result of administration of potent psychotropic agents. If NMS is not diagnosed early and vigorously treated in a fully equipped intensive care unit,6,7 then the condition can be fatal or give rise to permanent morbid sequelae. In this regard, what are signs and symptoms of neuroleptic malignant syndrome? Symptoms of neuroleptic malignant syndrome usually include very high fever (102 to 104 degrees F), irregular pulse, accelerated heartbeat (tachycardia), increased rate of respiration (tachypnea), muscle rigidity, altered mental status, autonomic nervous system dysfunction resulting in high or low blood pressure,Can antidepressants cause neuroleptic malignant syndrome?Neuroleptic malignant syndrome (NMS) is a rare complication of treatment with neuroleptics. An antidepressant-induced NMS is a very rare complication on the basis of pretreatment with neuroleptics causing chronic dopamine blockade and elevated plasma level of neuroleptics due to comedicated antidepressants.